Thymosin Alpha and Thymosin Beta 4 for DNA Damages Repair

Peptide Therapy is an exciting, cutting-edge medical science that uses specific amino acid sequences called “peptides” that, when properly administered, communicate with different parts of the body, potentially enhancing the function of the entire body by binding to receptors on the cell surface and signaling optimal messages for health improvement.

Thymosin Alpha

Thymosin alpha 1 is a peptide naturally occurring in the thymus that has long been recognized for modifying, enhancing, and restoring immune function. Thymosin alpha 1 has been utilized in the treatment of immunocompromised states and malignancies, as an enhancer of vaccine response.

Studies have postulated that thymosin alpha 1 could help improve the outcome in severely ill coronavirus disease 2019 patients by repairing damage caused by the overactivation of lymphocytic immunity and how thymosin alpha 1 could prevent the excessive activation of T cells.

Health Benefits of Thymosin Alpha

Thymosin alpha 1 functions as a toll-like receptor (TLR)-9 and TLR-2 agonist in both myeloid and dendritic cells, the professional antigen-presenting cells. By targeting TLRs, thymosin alpha 1 can stimulate the adaptive immune response, which is essential for fighting viral, bacterial, and fungal infections and cancers, as well as stimulating posterior humoral immunity.

Thymosin Beta 4

Thymosin-β4 is a small, actin-sequestering protein belonging to the thymosin-β family that is found at high concentrations within the spleen, thymus, and peritoneal macrophages, where it is most notably responsible for the organization of cytoskeletal structure.

Commonly found at significant quantities within the brain, lungs, liver, kidneys, testes, and heart, Thymosin-β4 has also been shown to be synthesized by cells unrelated to the reticuloendothelial system, such as myoblasts and fibroblasts, and expressed at irregular levels by several hemopoietic cell lines, malignant lymphoid cells, and myeloma cells. Recombinant Human Thymosin-β4 is a 5.2kDa glycoprotein containing 45 amino acid residues.

Benefits of Thymosin Beta 4

Thymosin beta 4 inhibits inflammation, microbial growth, scar formation (by reducing the level of myofibroblasts), apoptosis, and protects cells from cytotoxic damage, including glutamate neuronal toxicity. Thymosin β4 binds to G-actin, blocks actin polymerization, and is co-released with factor XIIIa by platelets. These activities contribute to the multiple wound-healing properties that have been reported in animal and human studies.

Awesome Thymosins for Cellular and DNA Repair

Thymosin Alpha 1 inhibits viral replication, stimulates stem cells, and aids in the production of new immune cells. Once it helps activate the immune system, it then helps kill bacteria, fungal, viral infections, and tumor cells. The immune system function is very critical to prevent disease and infection.

Thymosin Alpha 1 offers many benefits including:

immune-enhancing peptide;
helps prevent infections such as the common cold or the flu and diseases;
reduces inflammation in the body;
suppresses tumor growth;
aids in the removal of acute or chronic infections;
has antibacterial, antiviral, and antifungal properties;
supports the eradication of unhealthy cells (including cancer growth);
protects your cells against oxidative stress and damage;
inhibits viral replication;
improves symptoms associated with chronic fatigue.

Thymosin Beta-4 is a 43-amino-acid peptide that promotes healing throughout the body. It also has anti-inflammatory properties. Found naturally in higher concentrations at injury sites, the water-soluble protein can repair tissue damage and regulate cell migration to a site. It can improve wound healing and repair not only the skin, but also the brain, spinal cord, and heart.

In addition, TB4 has a low molecular weight and doesn’t bind to the extracellular matrix. This enables it to easily travel throughout body tissues, which promotes a faster rate of healing. The peptide travels long distances, so it usually doesn’t have to be injected directly at the injury site.

Thymosin Beta-4 is most often used by people looking to quickly recover from injuries. Athletes may use it to speed healing and get on the field sooner; they can also benefit from enhanced muscle growth, tone, and stamina. However, the peptide has numerous other benefits, ranging from improved muscle development and repair to stretching of connective tissues to improve flexibility, to the prevention of fibrous band formation in body tissues. It is also used to treat:

Arthritis: Effective in treating inflammatory conditions, TB4 can act on inflamed tissue and even help improve mobility by minimizing joint inflammation.

Blood clots: It has also been found to be effective at treating blood clots and promoting the growth of new blood cells.

Soft tissue damage: Injuries to muscles, tendons, and ligaments are more readily repaired when Thymosin Beta-4, which can also reduce scar tissue, is introduced.

Diseases: TB4 can help treat conditions such as autoimmune diseases and infections, as well as Lyme disease and traumatic brain injuries.

Muscular health: Improvements in the rate of muscle repair and growth have been noted, while it’s also possible to control muscle spasms.

Cardiovascular/neurological damage: TB4 has been found to promote new blood vessel formation, or angiogenesis, as well as neuron formation and improved axonal density in the brain.

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